Otolaryngology and ENT Surgery

Biography

Zhou Wu, PhD., is chair of department of Aging Science and Pharmacology, Faculty of Dental Science at the Kyushu University at Fukuoka, Japan. She graduated from medical college of Jilin University and worked as a clinic doctor for 10 years in China. She received her PhD from Kyushu University in 2001 and received postdoctoral fellow of Japan Society for the Promotion of Science (2002-2004) in Japan. After worked as an assistant professor in the Laboratory of Oral Aging Science (2004-2009), she promoted to associate professor in the Department of Aging Science and Pharmacology at the Kyushu University from 2010. Dr. Wu’s research is primarily focused on how systemic inflammation affects the onset and pathological process of Alzheimer’s disease at molecular and cellular levels. Dr. Wu's works is particularly interested in the functions of Cathepsins, the lysosomal enzymes, in innate and adaptive immunity, in particular how Cathepsins mediate pro-inflammatory molecule productions to amplify inflammation as well as in Aging andï€ Alzheimer’s disease. It is to be noted that Dr. Wu’s current works of clarifying the involvement of cathepsins in P. gingivalis- related periodontitis in onset and pathological process of Alzheimer’s disease. Dr. Wu’ s research is also interest in regulation of oxidative stress-related neuroinflammation, as well as systemic inflammation by nature production, which connect to innovate the early intervention approaches for prevention and clinic management of Alzheimer’s disease.

Research Interest

Aging, Alzheimer’s disease, neurodegeneration, microglia, neuroinflammation, free radical, oxidative stress, mitochondria, systemic inflammation