Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 4th International Conference on Rhinology and Otology Dubai, UAE.

Day 2 :

Session Introduction

Hitendra Prakash Singh

King George’s Medical University, India

Title: Recurrent meningitis: An unusual cause

Time : 11:15-11:50

Speaker
Biography:

Hitendra Prakash Singh has completed his Master of Surgery degree in ENT from Institute of Medical Sciences, BHU, Varanasi, India. He is presently working at King George’s Medical University, Lucknow, India as an Associate Professor. He has published more than 25 papers in reputed journals. His areas of interest are otology and head and neck cancer surgery.

Abstract:

Bacterial meningitis remains an existence debilitating disease even in the present anti-toxin time; thus, any abnormality which predisposes a patient to a recurrence of this serious disease must be identified and corrected. There have been numerous reports of meningitis due to congenital malformation of the inner ear. Recurrent bouts of meningitis are regular and acknowledgment of the internal ear as the source oftentimes comes simply after a few scenes have happened. Congenitally malformed inner ears may be a source of CSF otorhinorrhea. Two abnormal pathways must be present for any CSF leak to occur; one between the subarachnoid space and the inner ear and second between the inner ear and middle ear. The primary clinical importance of CSF leakage is the risk of meningitis. The presentation of such patients occurs in early stages of life. Authors hereby intend to present an unusual case of recurrent meningitis with common cavity malformation and fistula at stapes footplate, who presented to us at middle age. The patient was operated upon and became symptom free after the treatment.

Speaker
Biography:

Yang Xu is currently pursuing his PhD in West China School of Medicine, Sichuan University, China. He focuses on scientific research about rhinology and otology.

Abstract:

Background: Different delivery modes may affect the susceptibility to allergic diseases. It is still unknown whether early intervention with probiotics would counteract this effect.

Objectives: The effect of different delivery modes on immune status and nasal symptoms was investigated on established allergic rhinitis (AR) mouse model. In addition, the immunoregulatory effects and mechanisms of different feeding manners with Bifidobacterium breve were examined.

Methods: Live lyophilized B. breve was orally administered to BALB/c mice born via vaginal delivery (VD) or cesarean delivery (CD) for 8 consecutive weeks, after which they were sensitized by ovalbumin (OVA) to establish experimental AR. Nasal symptoms, serum immunoglobulins, cytokines, splenic percentages of CD4+CD25+Foxp3+ regulatory T(Treg) cells and nasal eosinophil infiltration were evaluated.

Results: Compared with VD mice, mice delivered via CD demonstrated more serious nasal symptoms, higher concentrations of OVA-specific immunoglobulin (Ig) E, more nasal eosinophil and lower percentages of splenic CD4+CD25+Foxp3+Treg cells after establishing experimental AR. These parameters were reversed by administering B. breves shortly after birth. However, the effect of B. breve did not differ between different delivery modes.

Conclusion: CD aggravates the nasal symptoms of AR mice compared to VD. This is the first report that oral administration of B. breve shortly after birth can significantly alleviate the symptoms of AR mice born via both deliveries, probably via activation of the regulatory capacity of CD4+CD25+Foxp3+Treg cells.

Yassin Pyar Ghulam Hussain

Al Ain Hospital, UAE

Title: Atrophic rhinitis

Time : 12:25-13:00

Speaker
Biography:

Yassin Pyar Ghulam Hussain has obtained his education in Otolaryngology and currently working as Specialist Physician in Al Ain Hospital in UAE.

Abstract:

Atrophic rhinitis is an uncommon and distinct clinical syndrome of progressive atrophy of the nasal mucosa. It is characterized by paradoxical nasal congestion and thick, troublesome nasal secretions and complicated by bacterial colonization and infection. Enlargement of the nasal cavities may occur in some forms. Most patients also have concomitant sinusitis and thus, the disorder is more accurately called atrophic rhinosinusitis. There are primary and secondary forms of this disorder, which affect different populations and have distinct presentations. This topic will discuss the classification, clinical manifestations, diagnosis and management of atrophic rhinosinusitis. Other forms of chronic rhinosinusitis are reviewed separately.

Speaker
Biography:

Abstract:

Background: In the field of rhinology, the majority of studies focus on mucosal immunology of the nose without giving attention to the underlying bones. Recent evidence indicates that the inflammation of chronic rhinosinusitis (CRS) is beyond the mucous membrane and involves the underlying bone of the paranasal sinuses as well. In the current study we tried to assess the prescence of osteitis in ethmoid bone and tissue eosinophilia in nasal mucosa of patients with chronic rhinosinusitis.

Patient and Method: A total of 85 patients (37 females and 48 males) who underwent surgery in our university hospital contributed to this study by providing bone samples from the ethmoid bone. They were divided into four groups: group I are Allergic Fungal Sinusitis (AFS) patients; group II are Chronic Rhinosinusitis patients without nasal polyp (CRSsNP); group III are Chronic Rhinosinusitis patients with nasal polyp (CRSwNP) and group IV are patients who underwent septoplasty as control group. Histological evaluation for osteitis (periosteal thickening and remodeling, osteoblastic and osteoclastic activity, and osteomyelitis and bone destruction) that was graded from 0 to IV, where grade 0 is normal histology and grade IV is frank osteomyelitis and bone destruction.

Results: Descriptive histology of the ethmoid bone analysis demonstrated osteitis of different grades in patients suffering from CRS: AFS patients; grade I (13.3%), grade II (46.7%), grade III (33.3%) and grade IV (6.7%). CRSsNP patients; grade 0 (10%), grade I (30%), grade II (40%), grade III (16.7%) and grade IV (3.3%). CRSwNP patients; grade 0 (10%), grade I (50%), grade II (20%), grade III (20%) and Control patients(DNS); grade 0 (70%), grade I (30%).

Conclusion: Herein, we show evidence of osteitis in CRS and confirm the presence of a higher grade osteitis in the AFS patients. This sinus bone remodeling may contribute to the chronicity of the disease and carries special consideration in the treatment of CRS.

Speaker
Biography:

 In 1982 Dr Yuri Nikolov graduated in Medical University of Pleven. Five years later he specialized "Ear, Nose Throat" and in 1991 he became a Phd. He specializes in St. Petersburg, Munich, Nice, Vienna, and Rome. He is a member of the Bulgarian Society of Otorhinolaryngology, also the European Academy of Otology since 2001 and American Academy of Otolaryngology, surgery of the head and neck since 2005. He has publications and participations in European and word Conferences and Workshops. 

Abstract:

In the last years, the using of a dynamic videoendoscopic analysis of the function of the Eustachian tube (ET) under conditions of changing pressure in the nasopharynx was shown that in 65% of cases of dysfunction of the Eustachian tube (ETD), the reason is in epipharyngeal tubal ostium. The most common factors bringing to narrowing the ostium of ET could be grouped as endonazal (inflammation with purulent reflux to the ostium, deformation and hypertrophy) and nasopharyngeal (hypertrophy of the tubal tonsils, of the torus tubarius and lymphoid tissue).The presence of this endonasal and nasopharyngeal pathology in chronic ETD reasonably raises the question of the effectiveness of the combination of radiofrequency (RF) tuboplastic and RF endonasal surgery, which is the objective of this work.Over a period of seven years have been made 210 (120 - m. 90 - f.) endoscopic RF tuboplastic surgery combined with RF endoscopic, endonasal surgery to remove the anatomical and chronic - inflammatory changes in the nasal cavity. All patients make a dynamic Videoendoscopie of the nasal cavity and the epipharinx and a complex of audiometry and tympanometry.The combination between the radiosurgical endonasal interventions and RF tuboplastc surgery gives very good results concerning the aeration of the middle ear, improvement of results audiometry and tympanometry in 85% of patients for follow-up period of 4 years.As a conclusion we can say that the treatment of chronic ETD should be aimed at restoring the-structure-functional unity of the ostium of the E.tube, as in our opinion the simultaneous RF endonasal operations combined with RF tuboplastic surgery appear to be a highly effective solution.

Yousif Alqahtani

Imam Abdulrahman Bin Faisal University, Saudi Arabia

Title: Sinonasal symptoms and outcome in pilots and Flight attendants
Speaker
Biography:

Yousif  Alqahtani is a 6th medical student at imam abdulrahman bin faisal  university, participate in many research and many campaign.

Abstract:

Sinonasal symptoms and outcome in pilots and  Flight attendants, Chronic rhinosinusitis (CRS) is a common medical condition, resulting in a considerable burden for both patients and health care providers. To determine the SINO-NASAL OUTCOME TEST (SNOT22) score and its  effect with flying hours in normal Air crew. This is a cross-sectional based questionnaire was conducted amoung 172 air crews randomly selected in Saudi Arabia. During the period from 24th may 2016 up to 24th august 2016.the survey included: demographic data,smoking,flying hours , effect on the job, (snot22) score and nasal surgery. The research included all Saudi air crews and excluded other air crews nationalities. The data was entered and analyzed by SPSS and chi-squared test. In result, the sample of the study is 172. 142 males(84%) and 27 (16%)females. 45.4% of air crews, their jobs are affected by sinonasal symptoms due to long hours of flying and 24.8% of them canceled their flight due to same problem. Most of the air crews (34.1%) fly more than 12 hours per flight.60% of the air crews complain of block nose and ear pain followed by nasal discharge. By using chi-square test ,there is a statistical  significant association between flying hours and nasal discharge (p = 0.012), ear fullness(p = 0.03) and nasal block(p = 0.004).In conclusion, Long flying hours have a significant risk of development many sinonasal problems such as nasal discharge ,nasal block and ear fullness . Therefore ,it is recommended to decrease the flying hours to the air crews.

Speaker
Biography:

Wang Jing is currently working toward her MD from West China Medical School, Sichuan University.
 

Abstract:

The objectives of this study are to investigate the relation between laryngopharyngeal reflux and chronic rhinosinusitis(CRS) and to explore the effect of pepsinA on the level of Heat Shock Protein (HSP)70. Nasal tissue specimens, nasal secretions and blood plasma obtained from 23 CRS patients with nasal polyps(CRSwNP) , 26 CRS patients without nasal polyps(CRSsNP) and 9 normal controls were studied, using Enzyme-Linked Immunosorbent Assay(ELISA) to measure pepsin levels in nasal secretions and blood plasma, Western analysis to measure Hsp70 and pepsinA levels in Nasal tissue specimens and Quantitative Real-time Polymerase Chain Reaction(Q-PCR) to detect the expression of pepsinogenA, HSPA5 and PTGS2 in Nasal tissue specimens.The expression of PepsinA in nasal secretions was significantly higher in patients with CRS than in normal controls(p<0.05). HSP70 expression level was significantly increased in pepsinA-positive turbinate mucosa, compared with controls (P<0.001) and pepsinA-negative turbinate mucosa in CRSwNP and CRSsNP patients (P<.001). Similarly, the HSP70 expression level was significantly increased in pepsinA-positive polyp tissues, compared with the controls (p =.021) and pepsinA-negative polyp tissues in CRSwNP patients (p =.016). There was no significant HSP70 expression difference between pepsinA-negative turbinate mucosa or polyp tissues and controls. Furthermore, no association was found between the presence of pepsinA and HSPA5 in Nasal tissue specimens.

The results suggest that the LPR may play a role in the development of CRS through the reflux of pepsinA. Increased expression of HSP70 may be associated with the pathogenic mechanism of pepsinA.

Speaker
Biography:

Al Azawi Ahmed is a Consultant Otolaryngologist with 20 years’ wide experience in the field of Otolaryngology Head and Neck Surgery, including 11 years’ experience in UAE from which almost 7 years he has worked in SEHA governmental hospitals. Presently, he has been working in Sheikh Khalifa General Hospital as a Consultant Otolaryngologist. He is involved in academic teaching as an Adjunct Assistant Professor as well as in scientific research. He is triple-board certified and a Fellow of the American College of Surgeons and a Fellow of the European Board and the Arab Board in Otolaryngology-Head & Neck Surgery.

Abstract:

For centuries, the diagnosis and treatment of deep neck abscesses have challenged physicians and surgeons. The complexity and the deep location of this region make diagnosis and treatment of infections in this area difficult. These infections remain an important health problem with significant risks of morbidity and mortality. Drainage is the cornerstone of therapy for the treatment of deep neck space abscesses after ensuring a secure airway before initiating any procedure. Between October 2010 and March 2013, 19 patients presented to the emergency department at Al-Ain Hospital with different varieties of deep neck abscesses. All of them underwent imaging test (either CT scan or ultrasound) to confirm the diagnosis and localization of the abscess. The decision for percutaneous drainage was based on a consensus between both ENT surgical and radiology teams. All patients were admitted to the hospital and received IV broad-spectrum antibiotics covering both aerobic and anaerobic bacteria. In an interventional radiology suite, ultrasound guided aspiration and catheter drainage of neck abscess was done under local anesthesia by insertion of a thin (6-8 Fr) trocar-type pigtail drainage catheter in the abscess cavity. The catheter was kept in place with frequent saline irrigation until drainage stopped. In 17 (89.5%) patients, the abscess was successfully drained and completely cured. In 2 (10.5%) cases the collection was still present after IRPD due to deep multiloculated abscess and required surgical drainage in the operative theater under general anesthesia. By minimizing the physical trauma to the patient, IRPD can reduce recovery time as well as shorten hospital stay. IRPD seems to be a fast, safe and highly effective low-cost minimally invasive method for treatment of deep neck abscesses. Neck abscesses that cannot be treated or not resolved with IRPD require surgical drainage in the operating room.

 

Saied Alhabash

Medcare Hospital Sharjah, UAE

Title: Maxillary cysts: The endoscopic approach

Time : 15:10-15:45

Speaker
Biography:

Saied Alhabash has obtained his education in Otolaryngology from Damascus Academic Hospitals under the Ministry of High Education and later joined as an Assistant Professor (Demonstrator) in the ENT Department, Almwasat Hospital and Alassad University Hospital. He has worked as a Supervisor in Neurosurgery Department in Damascus Hospital (Endoscopic Skull Base Surgery) and then as Supervisor in ENT Department in Red Crescent Hospital, Mediclinic Beach Road and Welfare Hospital, Canadian Specialty Hospital in Dubai, Zulekha Hospital, Sharjah Corniche Hospital and Amina Hospital. Presently, he is working in Medcare Hospital Sharjah, Dubai.

 

Abstract:

Endoscopic endonasal technique is very effective for treating many kinds of maxillary cysts including dentigerous and other kinds. The aim is to collect many cases of maxillary cysts in our ENT department and determine which of them can be treated endoscopically or by combined approach. Many Maxillary cysts can be approached endoscopically when there is any attachment with maxillary sinus and can be treated by a combination of open and endoscopic techniques. Endoscopic endonasal surgery could be considered as very promising way for dealing with maxillary cysts.

Speaker
Biography:

Lilian Felipe has worked as a PhD Researcher in Health Sciences in the field of Audiology and Otoneurology in Brazil and Netherlands. She has experience in the field of audiology and vestibulogy. Her research interests are audiology diagnosis and treatment, vestibular system (evaluation and treatment of dizziness), elderly, public/social health. Currently, she is a Coordinator and Chair Professor in Fluminense Federal University at the Speech Therapy and Audiology Department.

Abstract:

Schistosomal myeloradiculopathy (SMR) is the most severe and disabling form of schistosomiasis. The diagnosis is based on clinical, laboratory and image data. Vestibular-evoked myogenic potential (VEMP) is a neurophysiologic test that assesses the vestibulospinal pathway through acoustic or galvanic stimuli. The aim of this study was to evaluate cervical spinal abnormalities in patients with SMR. Fifty-two (52) subjects were evaluated, of whom 29 had SMR and 30 did not (normal control). Normal VEMP was observed in all volunteers without SMR. Abnormal VEMP was recorded in 34% of the group with SMR. After treatment, abnormal VEMP was found in 80% of those with persistent neurologic abnormalities. VEMP is a functional test and the alteration may precede image abnormalities. This procedure may be useful for early diagnosis of schistosomal cervical spinal cord involvement.

Speaker
Biography:

Manuele Casale has worked in Thomas Starzl Transplantation Institute in Pittsburgh, Humber River Hospital and the Hospital for Sick Children in Toronto, University Hospital in Sofia and House Ear Institute in Los Angeles. He has attended the 20th Advanced Course of Surgical Anatomy and Dissection in Otology, the Course of Surgical Anatomy, Microsurgery Intranasal Endoscopic Anterior Skull Base at the University of Zurich and Masters in Head and Neck Surgery at the National Cancer Institute Regina Elena in Rome. He carries out research on several topics which include molecular biology, clinical research and innovative design tools in otolaryngology.

 

Abstract:

Background & Aim: This study was designed to prospectively evaluate the role of nebulized hyaluronic acid (HA) as a treatment for patients with rhinitis medicamentosa (RM). RM is a pathological condition of the nasal mucosa induced by prolonged, excessive or improper use of topical decongestants.

Methods: Twenty-five (25) patients were treated with HA nebulized via Spray-sol twice a day (morning and evening) for 10-days (T1). Subsequently, after three days of washout, patients were treated with physiological saline nebulized via Spray-sol twice a day (morning and evening) for 10 days (T2).

Results: The HA Spray-sol treatment group significantly improved visual analogue scale (VAS) scores, whereas there was no statistically significant difference in the saline Spray-sol treatment group, results confirmed by the anterior active rhinomanometry (AAR) data. An improvement in the Global Rhinitis Score (GRS) was recorded in both groups, but plus in HA Spray-sol treatment group. Both groups showed a significant reduction in mucosal edema and nasal secretions. Patients treated with HA Spray-sol reduced or even eliminated (11/25 patients) the use of topical decongestant within 10 days of treatment with HA.

Conclusion: The results of this study suggest nebulized topical 9-mg sodium hyaluronate plays a pivotal role in the management of RM.

 

Speaker
Biography:

Yuri Tzvetanov Nikolov has graduated from Medical University of Pleven in 1982. He has specialized in Ear, Nose and Throat and has completed his PhD in 1991. He is a Member of the Bulgarian Society of Otorhinolaryngology, also the European Academy of Otology since 2001 and American Academy of Otolaryngology, Surgery of the Head and Neck since 2005.

Abstract:

In the last years, the using of a dynamic videoendoscopic analysis of the function of the Eustachian tube (ET) under conditions of changing pressure in the nasopharynx was shown that in 65% of cases of dysfunction of the Eustachian tube (ETD), the reason is in epipharyngeal tubal ostium. The most common factors bringing to narrowing the ostium of ET could be grouped as endonasal (inflammation with purulent reflux to the ostium, deformation and hypertrophy) and nasopharyngeal (hypertrophy of the tubal tonsils, of the torus tubarius and lymphoid tissue). The presence of this endonasal and nasopharyngeal pathology in chronic ETD reasonably raises the question of the effectiveness of the combination of radiofrequency (RF) tuboplastic and RF endonasal surgery, which is the objective of this work. Over a period of seven years; there have been made 210 (120: Males and 90 Females) endoscopic RF tuboplastic surgery combined with RF endoscopic, endonasal surgery to remove the anatomical and chronic inflammatory changes in the nasal cavity. All patients make a dynamic videoendoscopy of the nasal cavity and the epipharynx and a complex of audiometry and tympanometry. The combination between the radiosurgical endonasal interventions and RF tuboplastc surgery gives very good results concerning the aeration of the middle ear, improvement of results audiometry and tympanometry in 85% of patients for follow-up period of 4 years. As a conclusion we can say that the treatment of chronic ETD should be aimed at restoring the structure-functional unity of the ostium of the Eustachian tube, as in our opinion the simultaneous RF endonasal operations combined with RF tuboplastic surgery appear to be a highly effective solution.

Speaker
Biography:

Figen TT has completed his PhD at the age of 27 years from Ondokuz Mayıs University and postdoctoral studies from Cumhuriyet University School of Medicine. She studied about Mamografi in Adnan Menderes University, Department of Radiology.     
 

Abstract:

Frequent and broad application of endoscopic sinus surgery (ESS) in parallel with experience makes it imperative to know the anatomy and the existing pathology very well before surgery. This study examines the association between anomalies in the sphenoid sinus area in paranasal sinuses computed tomography (PNS-CT) and pathological findings and determines variations of sphenoid sinus. A total of 200 cases (100 women, 100 men) who had PNS-CT in the emergency and radiology polyclinics within the period of one year were included in this study. Bone tissue anomalies and soft tissue pathologies were assessed in the CT. Pterygoid process was found in 36.75% of our cases, anterior clinoid pneumatization was found in 21.25%; vidian canal in 34.25%, foramen rotundum in 17.5% and ICA in 12.75% had protrusion into the sphenoid sinus; 8.25% were found to have onodi cell, 11.25% were found to have multiple septation, 16.75% were found to have mucosal thickening and 2.5% were found to have retention cyst. The importance of PNS-CT in terms of determining anatomic variations before ESC and predicting possible complications during surgery has been emphasized once more. In our study, as sphenoid sinus pneumatization increased, the projection of neighbouring vein and nerve structures into the sinus was found to increase as well.

Speaker
Biography:

Bouali Mustapha is a ENT doctor fron Oran University Hospital. His main research is on head and neck surgery.

Abstract:

 Langerhans cell histiocytosis (LCH) is a group of three rare diseases (annual incidence less than 4/1000.000 H) with increasing aggressiveness respectively: Eosinophilic granuloma (unifocal solitary osteolytic lesion), Hand-Schuller-Christian disease (multifocal lesion) and Letterer-Siwe disease (the most aggressive, disseminated disease with systemic manifestations). The bone is the most commonly involved with a predilection for the skull. Some cases of temporal bone localisations have been described in the literature. We report a case of an 18 month child presenting a LCH of the temporal bone misdiagnosed at the beginning as an otoantritis. In fact, the child presented a retro-auricular swelling with inflammatory characters, fever and otorrhea. The exploration before surgery revealed besides the extensive temporal lesion, hematologic perturbations, a splenomegaly and a hepatomegaly. The histopathology confirmed the diagnosis of a LCH. We describe the diagnosis challenges, the surgical difficulties and the therapeutic response of the child and give a review of what was published on LCH and Letterer-Siwe disease.

Hitendra Prakash Singh

King George’s Medical University, India

Title: Recurrent Meningitis: An Unusual Cause

Time : 11:15-11:50

Speaker
Biography:

Dr. Hitendra Prakash Singh has completed his Master of Sursery in ENT from India’s premier medical institution Institute of Medical Sciences, BHU, Varanasi, India. He is presently working at King George’s Medical University, Lucknow, India as associate professor. He has published more than 25 papers in reputed journals. His areas of interest are otology and Head-neck cancer surgery.
 

Abstract:

Bacterial meningitis remains an existence debilitating disease even in the present anti-toxin time; thus, any abnormality which predisposes a patient to a recurrence of this serious disease, must be identified and corrected. There have been numerous reports of meningitis due to congenital malformation of the inner ear. Recurrent bouts of meningitis are are regular and acknowledgment of the internal ear as the source oftentimes comes simply after a few scenes have happened.Congenitally malformed inner ears may be a source of CSF otorhinorrhea. Two abnormal pathways must be present for any CSF leak to occur; One between the subarachnoid space and the inner ear, Second between the inner ear and middle ear. The essential clinical significance of CSF spillage is the danger of meningitis.The presentation of such patients occur in early stages of life. Authors hereby intend to present an unusual case of recurrent meningitis with common cavity malformation and fistula at stapes footplate, who presented to us at middle age. The patient was operated upon and became symptom free after that.

Hossam Thabet

Alexandria University, Egypt

Title: Branchial Arch Anomalies
Speaker
Biography:

Professor Hossam Thabet graduated from Alexandria University School Of Medicine (M.B.B.Ch )in 1980 with general grade of " Excellent with   honors”. He finished his  Master of Otolaryngology (M.Ch.ORL) in, 1984. He finished two years Clinical & Research Fellowship in Washington University (Barns Hospital), St Louis Missouri. USA  1988-1990. He got  his  Doctorate of Otolaryngology & Head and Neck Surgery in 1991. Hi is the head of the H&N Surgery Unit in Otolaryngology-H&N Surgery Department in Alexandria University. He has more than 35 publications in international & Egyption Journal

Abstract:

Branchial arch anomalies occur due to abnormal development of the branchial arch clefts or pouches. They may be in the form of a cyst, sinus, or fistula. Branchial cyst are the second common congenital pediatric neck swelling after thyroglossal duct cysts. Second arch branchial cleft cysts are the most common, they are  situated in the posterior submandibular space between the SMG  & SCM muscle. 3rd & 4th branchial arch cysts or fistulae are very rare. Branchial Cleft Cysts (BCC) with external openings are associated with the 1st  & 2nd  arches, whereas the 3rd & 4th  arches are associated with internal openings.

.

  • Rhinitis
Speaker
Biography:

Yang Xu is studying his PhD at the age of 25 years in West China School of Medicine, who is concentrating on scientific research about rhinology and otology.

Abstract:

Different delivery modes may affect the susceptibility to allergic diseases. It is still unknown whether early intervention with probiotics would counteract this effect. Objectives: The effect of different delivery modes on immune status and nasal symptoms was investigated on established allergic rhinitis (AR) mouse model. In addition, the immunoregulatory effects and mechanisms of different feeding manners with Bifidobacterium breve(B. breve) were examined. Methods: Live lyophilized B. breve was orally administered to BALB/c mice born via vaginal delivery (VD) or cesarean delivery (CD) for 8 consecutive weeks, after which they were sensitized by ovalbumin(OVA) to establish experimental AR. Nasal symptoms, serum immunoglobulins, cytokines, splenic percentages of CD4+CD25+Foxp3+ regulatory T(Treg) cells and nasal eosinophil infiltration were evaluated. Results: Compared with VD mice, mice delivered via CD demonstrated more serious nasal symptoms, higher concentrations of OVA-specific immunoglobulin (Ig) E, more nasal eosinophils and lower percentages of splenic CD4+CD25+Foxp3+Treg cells after establishing experimental AR. These parameters were reversed by administering B. breves hortly after birth. However, the effect of B. breve did not differ between different delivery modes. Conclusion: CD aggravates the nasal symptoms of AR mice compared to VD. This is the first report that oral administration of B. breve shortly after birth can significantly alleviate the symptoms of AR mice born via both deliveries, probably via activation of the regulatory capacity of CD4+- CD25+Foxp3+Treg cells.

 

  • Facial Plastic and Reconstructive Surgery
Speaker
Biography:

Ohoud is an intern , studied in king abdulaziz university the bacholar degree , collage of medicine  

Abstract:

Objective: To assess patients’ satisfaction about cosmetic and functional outcomes of uncomplicated rhinoplasty and the consequent psychological impact.

Methodology : A cross-sectional study carried out among patients aged ≥20years, who underwent primary functional and/or cosmetic rhinoplastic surgery at Al-Mashfa hospital, Jeddah. before January 2015 (1 year of postoperative follow-up).

A total 200 patients were randomly selected from the hospital database and contacted for an anonymous telephone interview using a validated, semi-structured questionnaire. Investigating 7 postoperative satisfaction parameters. The questionnaire was completed by 3 additional items scoring from 0-100 the overall nose function, appearance and patients’ mood before and after rhinoplasty; answers were analyzed as continuous variables

Results: We included patients who underwent functional(13.5%), cosmetic(20.5%) or both functional and cosmetic(66.0%) rhinoplasty. Satisfaction parameters showed highest satisfaction score for nose breathing followed by family and friends’ satisfaction about nose appearance, while willingness to change appearance through a new surgery had the lowest satisfaction score as 51.0% of the patients answered that they will undergo a new rhinoplasty for that purpose.

Female, divorced and unemployed patients had lower scores regarding satisfaction parameters, respectively, while no difference was observed by indication or educational level . Linear regression showed positive correlation of change in mood with both change in nose function and appearance.

Conclusions: Patients who underwent primary uncomplicated rhinoplasty have fair satisfaction about functional long-term outcomes but remain relatively dissatisfied esthetically especially female, divorced and unemployed patients. The extent of functional and cosmetic improvements have positive impact on the patient’s mood.

Session Introduction

Atieh Nazem

Tehran University of Medical Sciences, Iran

Title: Effect of therapeutic pulsed ultrasound on smell dysfunction in subjects with chronic rhinosinusitis

Time : 10:00-10:35

Speaker
Biography:

Atieh Nazem is currently pursuing MSc in Physical Therapy at Tehran University of Medical Sciences, Iran. She has two published articles to her credit. A certification of a poster from 27 th annual  congress of physical therapy association  in Tehran, Iran, Olympics Hotel 24-26 May 2016. A certification of recognition from 28 th  annual congress of physical therapy association and 1th international congress of physical therapy, Olympics Hotel 24- 26 may 2017.

Abstract:

Smell dysfunction is one of the main symptoms in chronic rhinosinusitis (CRS). Therapeutic ultrasound (US) is suggested as a novel method for treating the CRS. No study has evaluated the effect of therapeutic US in CRS. The aim of this study was to demonstrate the effects pulsed ultrasound (PUS) in CRS subjects with olfactory dysfunction. Eleven CRS subjects with smell dysfunction (mean age 47.90±4.6 years; male 7; female 4) participated in a pretest-posttest study design with 2 measurements before and after 10 treatment sessions and after one month follow up. Participants received pulsed US (1:9), frequency 1 MHz, intensity/duration 1 W/cm2/5 minutes and 0.5 W/cm2/4 minutes for the maxillary and frontal sinuses, respectively. Subjects underwent for 10 treatment sessions, three days a week with US given every other day. The outcome measures were the Persian versions of SNOT-20 and University of Pennsylvania Smell Identification Test (UPSIT). The repeated measures ANOVA were used for analysis. The mean changes of UPSIT scores (11/1 to 19/7) and SNOT-20 scores (41/4 to 19/6) were significantly improved after PUS therapy (p<0.001). At one month fallow up, the improvements were sustained. The pulsed ultrasound was effective in improving smell dysfunction and symptoms severity in this sample of patients with rhinosinusitis.

 

Speaker
Biography:

Ohoud Basim Al-Linjawi is currently an Intern at King Abdul-Aziz University, KSA. He has completed his Bachelor’s degree from the College of Medicine, King Abdul-Aziz University, KSA.

Abstract:

Objective: To assess patients’ satisfaction about cosmetic and functional outcomes of uncomplicated rhinoplasty and the consequent psychological impact.

Methodology: A cross-sectional study carried out among patients aged ≥20 years, who underwent primary functional and/or cosmetic rhino plastic surgery at Al-Mashfa Hospital, Jeddah before January 2015 (1 year of postoperative follow-up). A total 200 patients were randomly selected from the hospital database and contacted for an anonymous telephone interview using a validated, semi-structured questionnaire investigating 7 postoperative satisfaction parameters. The questionnaire was completed by 3 additional items scoring from 0-100, the overall nose function, appearance and patients’ mood before and after rhinoplasty; answers were analyzed as continuous variables

Results: We included patients who underwent functional (13.5%), cosmetic (20.5%) or both functional and cosmetic (66.0%) rhinoplasty. Satisfaction parameters showed highest satisfaction score for nose breathing followed by family and friends’ satisfaction about nose appearance, while willingness to change appearance through a new surgery had the lowest satisfaction score as 51.0% of the patients answered that they will undergo a new rhinoplasty for that purpose. Female, divorced and unemployed patients had lower scores regarding satisfaction parameters, respectively, while no difference was observed by indication or educational level. Linear regression showed positive correlation of change in mood with both change in nose function and appearance.

Conclusions: Patients who underwent primary uncomplicated rhinoplasty have fair satisfaction about functional long-term outcomes but remain relatively dissatisfied esthetically especially female, divorced and unemployed patients. The extent of functional and cosmetic improvements has positive impact on the patient’s mood.

 

Reham Rafei El-Shafei

Fayoum University, Egypt

Title: Audiovestibular profile of vestibular migraine patients

Time : 11:30-12:05

Speaker
Biography:

Reham Rafei El-Shafei has completed her MD in Audiovestibular Medicine from Cairo University and Postdoctoral studies from Cairo University and Fayoum University, School of Medicine, Egypt. She has been working in Audiovestibular Unit since 15 years; has 15 years of experience in diagnosis, treatment and rehabilitation of dizzy patients and hearing impaired patients, 3 years of experience in the treatment cochlear implant patients and 7 years teaching experience in Audiovestibular Medicine for undergraduates and postgraduates students.

Abstract:

Currently a new clinical entity which is vestibular migraine has become a very common disorder. The objective of our study is to describe the auditory-vestibular findings in vestibular migraine; which could play a major role in facilitating diagnosis and creating better awareness of the condition. This study included 50 adults which were divided into 2 groups: The cases group consists of 40 adults, suffering from vestibular migraine and the control group which comprised 10 adult migraineurs. The entire study group was subjected to basic audiological and vestibular assessment. The results showed 77.5% of bilateral within normal peripheral hearing within threshold level and 22.5% revealed hearing loss. Regarding vestibular assessment; all cases and controls were subjected to VEMP, VNG tests and SOT testing. The caloric test gave us the highest percentage of abnormal results 47.5%, followed by VEMP 30%. Positioning test revealed abnormality in 12.5%, positional test gave 5% abnormality and only 1 case showed down beating post head shakes. There appears to be no typical pattern in vestibular testing for establishing a diagnosis of vestibular migraine, which reinforces even further the need for a carefully taken clinical history and audiometric assessment.

Hossam Thabet

Alexandria University, Egypt

Title: Cervical Paragangliomas
Speaker
Biography:

Professor Hossam Thabet graduated from Alexandria University School Of Medicine (M.B.B.Ch )in 1980 with general grade of " Excellent with   honors”. He finished his  Master of Otolaryngology (M.Ch.ORL) in, 1984. He finished two years Clinical & Research Fellowship in Washington University (Barns Hospital), St Louis Missouri. USA  1988-1990. He got  his  Doctorate of Otolaryngology & Head and Neck Surgery in 1991. Hi is the head of the H&N Surgery Unit in Otolaryngology-H&N Surgery Department in Alexandria University. He has more than 35 publications in international & Egyption Journal

Abstract:

Paragangliomas are neuro-endocrine tumors of the extra-adrenal paraganglionictissues derived from neural crest and has been recognised as a part of the AminePrecursor Uptake and Decarboxylation of Pearse (APUD) system. They are found in the head and neck region commonly as carotid body tumors, glomus jugulare, glomustympanicum, glomus vagale , and sympathetic paragangliomas. Surgical excision is the preferred treatment of head and neck paraganglioma. Safe surgical excision requires; good preoperative planning based on angiographic study and preoperative hemodynamic carotid & cerebrovascular flow studies, Wide surgical exposure, meticulous hemostasis assisted in selected cases by preoperative embolization, proximal and distal vascular control, careful dissection of all major neurovascular structures, & co-operation of a vascular surgeon skilled in carotid reconstructive techniques. 

Speaker
Biography:

Martha Nikolova graduated from Sofia Medical University in 2013. From 2014 she is working in University Hospital “Tsaritsa Joanna”, Sofia, in ENT Department as a resident. As well she has shifts in Emergency Department in ENT area. She has participations in Bulgarian and European Conferences and Congress. Till now she was working in ENT ward for kids and for Oncology and Head and Neck surgery. 

Abstract:

Chronic dysfunction of the Eustachian tube (ETD) with a failure in the ventilation of the middle ear becomes socially significant problem because it causes complications on more than 4% of the adult population in the world. As a result of ETD, chronic inflammatory and adhesion processes are developed in the middle ear. The purpose of this study was to evaluate the results of radiofrequency tuboplastic (RFETP) to solve problems with tubal pathology and the result of otological complications in patients with preserved membranes and those with mesotympanum perforations. A prospective clinical study was carried out at 76 (40 - m. 34 - f.) Patients with chronic multiple ETD treated conservatively and some otological surgery. In all of them RFETP was done with a using of a bipolar electrode, HFITT equipment and fiber optics with a transnasal access.  Objective parameters of functional tests for the E. tube patency and the ventilation of the middle ear showed a significant improvement in 68.4% of patients after 2 mounts (74% after 1 year). The function of a tube can be optimized in 70% of patients after removal of the pathological structures in the ostium of E. tube by RFETP, which is recommended in patients with abnormal ventilation of the middle ear.

Speaker
Biography:

Abstract:

Management of blow-out fractures (BOF) is addressed by different specialities which have a substantial difference in opinions. However, there is a wide consensus that patients with the potential for late enophthalmus development require early surgical intervention. If improperly diagnosed or treated, these fractures may lead to serious complications, usually diplopia, enophthalmus, hypoglobus, restriction of eyeball motility and disturbances in sensory innervations. The timing of treatment, surgical technique and type of reconstruction material used is debated. The key to successful surgical repair of these injuries are adequate exposure, complete visualization of the entire fracture and anatomic reconstruction of the defect.  The recently advocated combination of traditional transconjunctival approach and endoscopic transantral approach allows reduction and reconstruction under clear endoscopic vision without a facial skin incision.

Speaker
Biography:

Bibin Georgie Thomas , MASLP, is a Audiologist in the otolaryngology department, NMC Dubai.Bibin Georgie earned both his undergraduate degree and his Masters Degree from the University of Kannur and University of Mangalore. He is board certified in Audiology. To his credit, Bibin Georgie Thomas has Several National & International papers got selected for presentation which includes British voice association conference -2013, 39th annual symposium: care of the Professional voice, held in Philadelphia, USA,American speech & hearing association Annual Convention (ASHA) 2013 , ISHACON Chennai (2012) and XXXII World Congress of Audiology Brisbane in May 2014. In 2010rd KSB ISHACON held in Ernakulum (Kerala) (2010) which got best paper award. In 2014 he received South India's Best Audiologist Award from Amplifon and also Nominated for Charles Holland Award for Best Audiological practice in India (Amplifon) year 2015.

 

Abstract:

Ramsay Hunt syndrome occurs when a shingles infection affects the facial nerve near one of your ears. In addition to this, Ramsay Hunt syndrome can cause facial paralysis and hearing loss in the affected ear. The present study investigates the audiological features and auditory processing of patient with this syndrome.Investigating auditory processing skills using a series of behavioural and objective tests known to be sensitive enough to assess a 40 year old women using Behavioural tests such as speech perception in noise, gap detection, and duration pattern and objective tests like ABR, MLR responses and OAE.Investigations of the peripheral auditory system revealed a right moderate sensorineural hearing loss, Poor scores on speech perception in noise, gap detection and duration pattern. These results confirmed using objective tests where the absence of OAE, abnormal latencies and interpeak latencies of the ABR and absence of MLR.The results of the present case study focus on the presence of auditory processing disorders and audiological features suggested test shows presence of auditory processing disorder and cochlear and retro cochlear involvement. Thus, cautious investigations of audiological evaluation are necessary in these individuals.

Speaker
Biography:

Md Monjurul Alam has completed MBBS, FCPS (ENT) MS (Otolaryngology). He is a Professor,Dept.of Otolaryngology & Head-Neck Surgery.

 

Abstract:

Background: Endoscopic ear surgery is a emerging technique with advancement highlighting advantages over the traditional microscopic approach.In Bangladesh  we started doing myringoplasty since 2005 with otoendoscope and stopped due to few problems But again, since 2007,  all types of middle ear surgeries  with nasal endoscopes has been being done with bright , wide & clear view. We did different types of Transcanal Tympanoplasties, ossicluplasties, stapedotomies, also few cholesteatoma surgeries by endoscope.As Rigid endoscopy allows for wide-field view of the surgical field improved resolution with high magnification, and the ability to look around corners , enabling direct visualization of the hidden recesses including the retrotympanum, epitympanum, supratubal recess, peritympanum  and hypotympanum, granulation tissue or cholesteatoma matrix can be removed easily.

Methods: A cross sectional study  done during March,2010 to June,2014 in otolaryngology & Head-Neck surgery dept of Bangabundhu Sheik mujib Medical University (BSMMU) after having permission from Ehethical review board  of the University.

Results : During the study period 1200 different types of transcanal  Endoscopic  Tympanoplasties like underlay &  interlay tympanoplasty using different graft matrials ;temporalis fascia,perichondrium, cartilage with graft taken up rate & hearing gain equivalent with tympanoplasty done by microscope. 517 different types ossicluplasties  and stapedotomies were done with similar hearing gain  done by microscope.117 cholesteatoma surgery – Atticotomy, attico-antrostomy with reconstruction have been done  without any major  complication or recurrence. Learning curve of surgery among the residents  is higher with endoscope.

Conclusions: Endoscopic ear surgery is a new technique which is gaining momentum in Bangladesh and there is enthusiasm for its incorporation into future practice.  Further investment in training courses and guidance for those who looking to start or advance the use of endoscopes in their practice will be vital in the the years to come.

Speaker
Biography:

Yang Xu is studying his PhD at the age of 25 years in West China School of Medicine, who is concentrating on scientific research about rhinology and otology.

Abstract:

Background: Different delivery modes may affect the susceptibility to allergic diseases. It is still unknown whether early intervention with probiotics would counteract this effect. Objectives: The effect of different delivery modes on immune status and nasal symptoms was investigated on established allergic rhinitis (AR) mouse model. In addition, the immunoregulatory effects and mechanisms of different feeding manners with Bifidobacterium breve(B. breve) were examined.

Methods: Live lyophilized B. breve was orally administered to BALB/c mice born via vaginal delivery (VD) or cesarean delivery (CD) for 8 consecutive weeks, after which they were sensitized by ovalbumin(OVA) to establish experimental AR. Nasal symptoms, serum immunoglobulins, cytokines, splenic percentages of CD4+CD25+Foxp3+ regulatory T(Treg) cells and nasal eosinophil infiltration were evaluated.

Results: Compared with VD mice, mice delivered via CD demonstrated more serious nasal symptoms, higher concentrations of OVA-specific immunoglobulin (Ig) E, more nasal eosinophils and lower percentages of splenic CD4+CD25+Foxp3+Treg cells after establishing experimental AR. These parameters were reversed by administering B. breves hortly after birth. However, the effect of B. breve did not differ between different delivery modes.

Conclusion: CD aggravates the nasal symptoms of AR mice compared to VD. This is the first report that oral administration of B. breve shortly after birth can significantly alleviate the symptoms of AR mice born via both deliveries, probably via activation of the regulatory capacity of CD4+- CD25+Foxp3+Treg cells.

Speaker
Biography:

Dr Kalpana Nagpal is a senior consultant in the department of ENT head and neck and Robotic surgery .She completed her graduation in medicine from Osmania medical college and MS in ENT from Armed forces medical college Pune India .She also has visiting fellowship in nose and sinus disease from memorial medical centre Savannah Georgia USA.Robotic surgery training from Seoul south korea .In addition she has done DNB ENT also in the year 1995.she has published frontal sinus rescue procedure in American journal of rhinology in1999.

Abstract:

Post tympanoplasty graft  mucolization leads to continuous discharging ear even after successful graft  uptake because of presence of mucous secreting glands on the lateral aspect of graft .Process of epitheliasation or mucolisation of margins of perforation  in the settings of chronic otitis media  is known .Total annulus excision is an interlay type of tympanoplasty where graft is kept between mucosa medially and canal skin epithelium laterally .The advantage of TAE(total annulus excision ) is complete excision of diseased tympanic membrane and no weeping neotympanium in future .excision of annulus also ensures rich neovascularization around the graft.The neoannulus is kept at original place to prevent anterior angle blunting .

Speaker
Biography:

She is a physicaltherapy student in MS.c cours at tehran university of medical science ,which is preparing the my MS.c program.she has been published 2 articles in view of rehabilitation in asthma diseases as a co-worker in the iranina medical science journals, as well, an article was accepted to present on the 1th intetnational congress of physical therapy in tehran ( title: Effect of Therapeutic Pulsed Ultrasound on Smell Dysfunction in Subjects With Chronic Rhinosinusitis  (2017) 

Abstract:

Smell dysfunction is one of the main symptoms in chronic Rhinosinusitis (CRS). Therapeutic ultrasound (US) is suggested as a novel method for treating the CRS. No study has evaluated the effect of therapeutic US in CRS.The aim of this study was to demonstrate the effects pulsed ultrasound (PUS) in CRS subjects with Olfactory dysfunction .

Eleven CRS subjects with smell dysfunction (mean age 47.90±4.6 yrs; male 7; female 4) participated in a pretest-posttest study design with 2 measurements before and after 10 treatment sessions, and after one month follow up. Participants received pulsed US (1:9), frequency 1 MHz, intensity/duration 1 W/cm²/5 minutes and 0.5 W/cm²/4 minutes for the maxillary and frontal sinuses, respectively. Subjects underwent for ten treatment sessions, three days a week, with US given every other day. The outcome measures were the Persian versions of SNOT-20 and University of Pennsylvania a Smell Identification Test (UPSIT). The repeated measures ANOVA were used for analysis.

The mean changes of UPSIT scores (11/1 to 19/7) and SNOT-20 scores (41/4 to 19/6) were significantly improved after PUS therapy (p<0.001). At one month fallow up, the improvements were sustained.

Conclusions: The pulsed ultrasound was effective in improving smell dysfunction and symptoms severity in this sample of patients with rhinosinusitis.

Speaker
Biography:

Sara Alqahtani  is a Medical Student.  

Abstract:

Functional endoscopic sinus surgery (FESS) is most commonly performed procedure for inflammatory and infectious sinus diseases including those of sphenoid. A rough guide to enter sphenoid ostium is the face of the sphenoid is approximately 7 cm from the nasal spine at a 30° angle from the horizontal and the superior turbinate aids in the confirmation of the sphenoid position in difficult cases.

Objectives: This study was conducted to find out the easiest fixed bony landmark for localizing the sphenoid sinus ostium for FESS and Pituitary Surgery so as to avoid injury to the internal carotid artery and the optic nerve which are the anatomically close to sphenoid sinus and are at risk during these surgical procedures.

Methods: It was a retrospective study in which computerized tomographic (CT) scan axial cut of sinuses from 166 patients were reviewed to determine average distance between Posterior Maxillary Wall (PMW) and the Front of Spehnoid (FOS) in both right and left sides.

Results: Mean age of the patients was 41.18±14.75 (95% CI = 38.92 – 43.44) years. Males (n=88, 53.01%) and females (n=78, 46.99%) were almost equally participated in the study. The average anterior-posterior distance from the PMW to the FOS was on the right side 7.1mm and on the left side 7.9mm, the average in both right and left respectively was 7.5mm in the CT scans.

Conclusions: The posterior maxillary sinus wall may act as a concrete and unmistakable bony landmark on CT scan to localize the face of sphenoid sinus for the sinus surgeons performing FESS and pituitary surgery.

Key words: Sphenoid, posterior maxillary wall, functional endoscopic sinus surgery, pituitary surgery

Speaker
Biography:

Dr sambhaji chintale has completed ms ent from Dvmgmc solapur   from muhs nashik  INDIA

Dr chintale is director  OF COSMO ENT SUPERSPECIALITY HOSPITAL AURANGABAD india  have published papers inmany reputed journals and also serving as an author of online journal of otorhinolaryngolgy also  work as reviewr for international journal 

Abstract:

Background: Local Anaesthesia is now being accepted universally as a safe alternative to generalanaesthesia for thyroid surgery. Aim: This study was carried out to compare the outcomes of patients undergoing thyroid surgery under local and general anaesthesia. Material and Methods: two atients who underwent thyroid surgery for benign and malignant diseases under local and generalanaesthesia from march 2014  to march  2017 were analysed. Patient characteristics analysedwere age, sex, pathology lesion size, operating time, length of stay, cost and post operative complications.Results: Mean lesion sizes were 5.26 cms. and 6.33 cms. in local and general anaesthesia group

respectively. Mean operating time was 41.6 minutes and 74.5 minutes in local anaesthesia and generalanaesthesia group respectively. Mean cost incurred was Rs.8000 in local anaesthesia and Rs.18000 in general anaesthesia group. Mean length of hospital stay was 39.26 hours and 71.06 hours in local anaesthesia and general anaesthesia group respectively. Conclusion: Local anaesthesia is a safe alternative to general anaesthesia for patients undergoing thyroid surgery. Use of local anaesthesiahas resulted in a decreased length of stay, cost and mean operating time, hence useful in a setup ithlimitedanaesthesia time and increased work load.

Key words: Local anaesthesia, thyroid surgery, general anaesthesia

Speaker
Biography:

Nitin Arora has completed his MBBS degree, at the age of 23 years from GMC, Patiala, Punjab ,India and is currently pursuing his MS degree, from Baba Farid university of health sciences,(Faridkot) Punjab, India.

He has presented many oral and poster presentation in various state and national level conferences and has won post graduate quiz twice in Punjab state conference

Abstract:

Bone destruction seen in chronic otitis media mainly involves the ossicles, incus being frequently involved ossicle. So, an investigation of the histopathological changes in incus from CSOM patients was carried out, and was compared with histology of normal incus taken from  cadavers with normal TM.

Materials and Methods: Ten normal incuses and ten pathological incuses which were removed during the surgery for chronic otitis media (both with and without cholesteotoma) were studied histologically, after staining with haematoxyline and eosin.

Results: Normal incus showed compact bone pattern of concentric rings, like that of any long bone of body. Pathological incuses of chronic otitis media (both with and without cholestoetoma) showed similar changes, i.e stratified squamous epithelium, with distorted concentric rings and increased osseous spaces.

Conclusion: the study was undertaken, so that the knowledge to histological changes may help the clinicians to take more rational decisions regarding their diagnosis and therapeutic interventions to prevent the changes occurring in the bone in COM.